First principles, Clarice. Simplicity. Read Marcus Aurelius. Of each particular thing ask: what is it in itself? What is its nature? - Hannibal Lecter
People needlessly suffer hangovers, and yet hangovers are avoidable and mitigatible First ask: What is a hangover?
A hangover is the feeling a person has when his brain suffers minor neurotoxicity, hypoglycemia, electrolyte imbalance, and vitamin B deficiency. That is its essence.
Vitamin water, alpha lipoic acid, and Vitamin B12. Here's a brief explanation before beginning my staycation.
Vitamin water (I use Vita Coco) is perfect. It is used as an IV, i.e., as a saline solution, because it has the electrolyte balance a person needs to prevent dehydration. Before going out (and before going to bed), I drink a vitamin water. There are many brands, so read the labels. NO SUGAR ADDED. You want pure vitamin water. The kind with pulp grosses me out, so here's the brand I use.
It's a lot cheaper than gas-station gatorade, which is just a bunch of high fructose corn syrup and also has an inferior electrolyte profile.
Alpha lipoic acid is the most important nutritional supplement a person can take. It's clears glucose from the bloodstream, and also protects the brain from toxicity. If you ever roll x/MDMA, alpha lipoic acid will save you ass. Here's a fancy way of saying, "avoiding the Tuesday blues."
Repeated administration of the metabolic antioxidant alpha-lipoic acid (100 mg/kg, i.p., b.i.d. for 2 consecutive days) 30 min prior to MDMA did not prevent the acute hyperthermia induced by the drug; however, it fully prevented the serotonergic deficits and the changes in the glial response induced by MDMA.
I take 200 mg. of ALA before leaving the house. I take several capsules with me, and take 200 mg. after every second drink. NOW foods is a good brand, as is AST Sports. I just price watch them on Amazon, and swoop when the prices drop.
Vitamin B12 is all the same. Find the cheapest one.
Take a B complex before going up, and before bed.
I have friends coming into town, and am going to put the above hangover cure to good use. Have a great weekend.